Stoke Therapeutics (Nasdaq: STOK), is a biotechnology company dedicated to addressing the underlying cause of severe diseases. The company is pursuing an entirely new approach to treating severe diseases. We are initially focused on diseases of the central nervous system and the eye, with an emphasis on haploinsufficiencies, which are diseases caused by a loss of about half of the normal protein levels. Rather than replace, repair or edit faulty genes, we aim to increase – or stoke – protein output from healthy genes to restore functional protein levels using our proprietary TANGO (Targeted Augmentation of Nuclear Gene Output) platform. In all, Stoke has identified ~6500 genes with a TANGO signature, representing broad potential for our approach to help people with severe diseases.
We recently announced landmark data that support the potential for STK-001 to be the first disease-modifying medicine for Dravet syndrome, a severe and progressive genetic epilepsy that is characterized by frequent, prolonged and refractory seizures, beginning within the first year of life. The disease is classified as a developmental and epileptic encephalopathy due to the developmental delays and cognitive impairment associated with the disease.
Stoke is also advancing STK-002, a potential treatment for autosomal dominant optic atrophy (ADOA), the most common inherited optic nerve disorder. Currently there are no approved treatments for ADOA. Clinical studies of STK-002 are anticipated to start in 2024. The company is pursuing potential new medicines for three additional neurodevelopmental disorders, including Syngap1 and Rett syndrome, in collaboration with Acadia Pharmaceuticals.
Position Purpose:
The Manager, FP&A will play a critical role in financial and strategic decision making at the Company and therefore play a key role in the future growth of the company. The focus of this position will be managing the budgeting, forecasting and long-range planning processes as well as serving as the business partner to all departments. This person will work closely with team members and department heads throughout the company to understand and manage the performance of their respective areas. This position will be a partner to and interact closely with the rest of the finance team as we analyze spend and financial performance.
This individual will develop and own the Company’s internal financial model and update continuously as budgets are updated, business needs change, and other strategic considerations need to be reflected in Stoke’s financial model. This team member will conduct financial quarterly forecasts, annual budgeting updates, and operating plan variance analysis while driving the annual long-range planning process and special projects. S/he will provide financial consulting and strategic support to senior management including preparing board presentations, financial presentations, capital expenditure analysis, industry/peer group comparisons, new business opportunities, acquisition analysis and other projects requested by senior management and the Board of Directors. The position reports to the Chief Financial Officer.
Key Responsibilities:
- Develop and own the annual budgeting process and quarterly rolling forecast.
- Provide regularly recurring reports that summarize operational results and forecasts, including department performance against financial, strategic and operational targets, with timely communication of opportunities and risks to relevant stakeholders; routinely communicate business, financial, and operational performance trends, historical and forecasted, using appropriate metrics.
- Execute as lead financial reporting preparation of annual, quarterly, monthly management reporting dashboards at corporate, functional, program, and account levels.
- Identify, interpret and explain budget and expense variances: analyze cost variances, actual vs. plan/forecast and actual vs. prior period, review with departments.
- Actively partner with departments to ensure accurate monthly financial reporting and provide ongoing financial and analytical support.
- Collaborate with the VP of Finance to ensure consolidations adhere to tight timelines and controls as required by SOX guidelines; support Accounting in the monthly close process/accruals, Budget vs Actual analysis and access to results.
- Develop and implement forecasting models for both planning and accrual recognition.
- Provide financial support to the leadership team to create financial presentations toward business operations for Board prep.
- Implement Best Practices/ Policies as defined by internal and external guidelines.
Required Skills & Experience:
- B.A. or B.S. degree.
- 3-5 years of financial planning and analysis experience with progression demonstrated, preferably within the biopharmaceutical space.
- Advanced Microsoft Excel and PowerPoint skills required.
- Self-motivated, strategic and analytical thinker with superior problem solving and decision-making skills.
- Ability to work independently and collaboratively, as required, in a fast-paced start-up environment consisting of internal and external team members.
- Strong work ethic and a team player.
- Strong quantitative and financial modeling skills; experience with the development of comprehensive valuation models in Excel.
- Superior project management and communication skills, both written and verbal, including the ability to support and prioritize multiple projects.
- Ability to pivot and work successfully in a fast-paced environment.
Location(s):
Stoke operates sites in Bedford, MA, and Cambridge, MA. This position is a hybrid position with an office setting based in our Bedford, MA location.
Culture & Values:
At Stoke, we believe that innovation, the ability to successfully advance our ground-breaking science and having fun as a team are enhanced by being together in person, at least periodically. We allow for flexibility in work arrangements that balance individual’s needs and preferences with the needs of our business and our desire to foster a culture of collaboration and innovation.
Our values guide our work to deliver meaningful medicines for people who need them. We are committed to being true to ourselves, to our colleagues, and to the people with severe diseases who are counting on us. We embrace diversity within a unique culture that is defined by our values. Our employee-led Diversity, Inclusion, and Belonging Committee (DIB) underscores the importance of DIB to who we are and what we do.
Benefits & Compensation:
At Stoke Therapeutics we are proud to offer comprehensive and competitive employee benefits, including medical, dental and vision insurance; life, long and short-term disability insurance; Paid Parental Leave; a 401K program with company match, unlimited vacation time, and an Employee Stock Purchase Program (ESPP). Compensation is market competitive for the industry and directly commensurate with experience. All positions are bonus and stock eligible.
Interested candidates: Please visit Stoke’s website to learn more and apply directly to the position listed on our Career Center:
For more information, visit https://www.stoketherapeutics.com/ or follow the company on Twitter at @StokeTx.
