Computation is revolutionizing drug discovery. Advances in big chemical data, massive computing power, artificial intelligence, and molecular dynamics simulation are changing the way we develop new drugs. At 1910 Genetics, we put computation at the heart of drug discovery, blending expertise in computational chemistry, structural biology, pharmacology, genetics, data science, and software engineering to develop drugs for previously undruggable targets.
1910 Genetics is seeking a Head of Platform Technology, who would be responsible for producing best-in-class, high quality, and proprietary wet lab data sets that are purpose built for 1910's AI platforms - SUEDE (AI-driven ultra large scale virtual screening for Novel Hit Discovery), BAGEL (AI-driven generative chemistry for Hit to Lead), QAPTAIN (Quantum ML platform for lead validation), and MOTOWN (AI-driven ADMET predictive modeling for lead optimization).
Responsibilities:
- Wet Chemistry: synthetic route planning, molecule synthesis, analytical characterization, compound management, and management of external chemistry CROs.
- Wet Biology: robotics, automation, in vitro assays (target-based and phenotype-based biochemical and cell-based assays), and in vivo assays (PK, PD, and PK/PD).
Qualifications:
The ideal individual has a PhD in Biochemistry, Medicinal Chemistry, or Organic Chemistry and 15+ years of industry experience leading automation and high throughput biology/chemistry for target ID, Novel Hit Discovery, Hit to Lead, and Lead Optimization campaigns across multiple target classes and disease areas as a member of the senior leadership team of a small to mid-stage biotech company or the R&D organization of a large pharmaceutical company.
Compensation & Benefits:
- Extremely generous equity package coupled with competitive salary.
- Healthcare benefits.
- Generous vacation and parental leave.
- Super cool team building activities.
- Flexible work schedule.
- Great colleagues.
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