Kyowa Kirin is a fast-growing global specialty pharmaceutical company that applies state-of-the-art biotechnologies to discover and deliver novel medicines in four disease areas: bone and mineral; intractable hematologic; hematology oncology; and rare disease. A Japan-based company, our goal is to make people smile by delivering breakthroughs where no adequate treatments currently exist, working from drug discovery to product development and commercialization. In North America, we are headquartered in Princeton, NJ, with offices in California, Massachusetts, and Ontario.
Summary:
The Senior Research Scientist purpose is to display leadership, technical and analytical expertise in pharmacologic evaluation of cell and gene therapy research to make the project success.
Essential Functions:
- Plan, supervise, conduct, and/or participate in in vivo pharmacologic studies in CGT research project.
- Provide advice to project leaders on pharmacological evaluation.
- Contributes to non-clinical development (pharmacology part of regulatory filings) for cell and gene therapy projects.
- Prepares documentation including proposals, reports, patent applications, publications, animal/biosafety/human subject protocols etc.
- Independently directs, manages and executes pharmacology studies for multiple projects.
- Provides education and training to team members on the knowledge and skills required for pharmacology study of CGT.
- Establishes daily or weekly plans of the team members necessary to meet project timetables and project advancement.
- Keeps up to date on advanced technologies for cell and gene therapy research and actively applies new concepts as appropriate to improve capabilities.
- According to the company's goals, participates in decision-making regarding research plans and strategies.
- Provides information to develop team or project-related budget for capital equipment, contract research, and critical supplies and manages project related costs.
- Identify issues within the team/organization, consider and implement measures to resolve them.
- Manages CRO or other outsourced pharmacology studies.
Requirements:
Education
Ph.D. and/or MD degree in oncology, hematology or closely related discipline.
Experience
- A minimum of eight (8) years bio pharmaceutical industry experience with a focus on in vivo pharmacology evaluation of cell and gene therapy projects in the heme-oncology, hematology, autoimmune disease or rare disease space.
- Extensive knowledge and experience of cell and gene therapy research, especially in vivo evaluation system and disease models.
- Experience in leading, planning and conducting pharmacological studies for IND application of cell and gene therapy projects, including in-house and outsourced studies.
- Demonstrated leadership and management in a cross-functional global team setting.
- Proven experience in managing and mentoring Research Associates of various disciplines.
Technical Skills
- Broad knowledge base in hematology, oncology and immune-related diseases.
- In-depth knowledge and experience with in vivo evaluation of cell and gene therapy drug candidates in disease models.
- Knowledge and experience necessary to design and execute preclinical in vivo studies for the development of novel cell and gene therapy.
- Strong written, verbal, and listening communication skills: articulate and effective communicator and presenter, able to describe complex problems and solutions in understandable terms; Ability to take complicated scientific concepts and effectively communicate them to a range of audiences.
- Outstanding interpersonal skills that enable inclusion of people across the internal and external organizations to make efficient collaboration.
Annualized base salary ranges from $140,000 - $165,000 plus short term incentive bonus; actual salaries will vary and may be above or below this range commensurate with various factors including but not limited to experience, education, training, and merit.
KKNA and all of its employees have an obligation to act in accordance with the law and with integrity in all our operations and interactions.
It is the policy of Kyowa Kirin North America, Inc. to provide equal employment opportunity to all qualified persons without regard to race, religion, creed, color, pregnancy, sex, age, national origin, disability, genetic trait or predisposition, veteran status, marital status, sexual orientation or affection preference or citizenship status or any other category protected by law.
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