Scientist, Antibody Discovery & Engineering
We’re in relentless pursuit of breakthroughs that change patients’ lives. We innovate every day to make the world a healthier place.
To fully realize Pfizer’s purpose – Breakthroughs that change patients’ lives – we have established a clear set of expectations regarding “what” we need to achieve for patients and “how” we will go about achieving those goals.
As a Scientist, you will be at the center of our operations and you’ll find that everything we do, every day, is in line with an unwavering commitment to quality. You will be part of Pfizer's Worldwide Research and Development team that employs a multidisciplinary approach to identify cancer targets and develop next generation Oncology therapeutics and therapeutic combinations. You will contribute to cell engineering and antibody discovery for the development of novel biotherapeutics. You will be responsible for extensive molecular biology, tissue culture and cell biology benchwork, including vector engineering, Polymerase Chain Reaction (PCR), cloning, cell engineering, flow cytometry, and assay development. You will also contribute to molecular analyses of cancer targets, antibody sequencing and identification of sequence liabilities.
With your deep knowledge in the discipline, you will be an active team member who influences at the project team level. You will be using your scientific judgment to adapt standard methods and techniques by applying prior work experience and consulting others. Your ability to plan will help in preparing short-term work activities on projects. Your creativity in developing novel processes and new ideas will be used frequently. You will undertake mentoring activities to guide your team members.
It is your innovative scientific temperament that will help in making Pfizer ready to achieve new milestones and help patients across the globe.
ADDITIONAL POINTS:
- Contribute to achievement of goals and influence at the project team level
- Provide cell engineering and molecular biology support for multiple Oncology Research projects
- Evaluate data and provide clear reports that can be shared and transferred to and from cross-functional teams
- Pay attention to detail, strictly adhere to safety protocols, and use knowledge of basic laboratory procedures to advance projects under rapidly shifting priorities and timelines
BASIC QUALIFICATIONS:
- Bachelor’s degree + 6 years laboratory research experience or Master’s degree + 4 years laboratory research experience in molecular and cellular biology or related subject
- Proficiency in culturing multiple cell lines under BSL2/BSL2+ conditions
- Experience with different cell engineering technologies, including transient transfection, lentiviral transduction, and CRISPR
- Experience with high-throughput multi-color flow cytometry and single-cell sorting
- Strong molecular biology skills, including primer design, PCR, plasmid generation, agarose gel electrophoresis, Sanger sequencing, and NGS library preparation
- Familiarity with sequence analysis tools, including online bioinformatics databases
- Demonstrated ability to work independently and collaboratively, adapting to project needs
- Ability to organize and prioritize work to meet timelines and deliverables
- Strong written and verbal communication skills, including ability to accurately document experiment data and present results
PREFERRED QUALIFICATIONS:
- Proficiency in quantitative flow cytometry
- Experience coding in Python, R, or other programming language
- Understanding of antibody biology and antibody drug conjugates (ADCs)
- Familiarity with Oxford Nanopore sequencing and data analysis
Other Job Details:
- Last date to apply is November 4, 2024
The annual base salary for this position ranges from $74,900.00 to $124,800.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 7.5% of the base salary. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits.
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