At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. R&D is committed to discovering and delivering transformational vaccines and medicines to prevent and change the course of disease.
We believe the Greater Boston area is an important hub for the biotech and pharma industry, which is why we’ve invested in growing our footprint and expanding our R&D space in Cambridge, with a primary focus on additional state-of-the-art lab space. Here, we will bring together talent and expertise, building upon GSK’s long history of vaccine development, to create globally leading viral capabilities and cutting-edge vaccines technologies, as we add to our robust portfolio targeting infectious diseases at every stage of life.
The Nucleic Acid Vaccines Center of Excellence (NAV CoE), a global team within the GSK’s Drugs Substance (DS) Vaccine’s Technical Research and Development organization, has as a mission to develop the next generation RNA Drug Substance vaccine platforms for rapid development of new vaccine candidates. It has branches in Rockville, MD, US (Cambridge, MA from 2025) and in Rixensart, Belgium.
We are looking for an RNA DS Platform Analytical Leader to join the NAV CoE and lead a global team of analytical scientists based in Belgium and the US with the objective of continuous development and optimization of RNA-based vaccine platforms, integrating the latest state-of-the-art technologies and paving the way to bring new vaccine candidates from development to the clinical manufacturing stages.
Based in the US or BE branch, this role will report to the Global Head of the NAV CoE and will play a significant role in shaping current and next generation GSK’s mRNA vaccine platforms to accelerate addressing unmet medical needs, a compelling field having a direct impact into patients and global health. This exciting opportunity allows you to lead key activities, collaborate with top talents in the vaccines industry, and advance your career while ensuring timely project delivery in collaboration with process development colleagues.
The candidate is also expected to spend few months (from 3 to 6 months) within the first year in Rockville (Washington DC area) to support and ensure a smooth transition of the methods and the knowhow to the new laboratories in Cambridge.
Key Responsibilities:
- Lead development of in process analytics comprising a team of ~5 analytical scientists split in 2 locations (US and Belgium) to facilitate RNA DS platform process development and continuous RNA platform evolution as new technologies and discoveries emerge in the field.
- Work closely with the Global Head of the NAV CoE for strategy definition, as well as with the Global RNA Platform Development Leader and the RNA Project Delivery Leader to drive excellence in process development and project execution.
- Work closely with the Analytical R&D team to share and ensure strategic alignment on technologies, method development and transfer between teams, to build a set of state-of-the-art robust methods and control strategy fit for each stage (development, clinical and/or commercial).
- Position as an opinion leader within the organization: think and act strategically, impact and influence within DS, across functions and at senior leadership level to continuously improve and shape a strategy & framework for a robust global fast mRNA production strategy.
- Embrace an open global mindset, fostering a positive culture of transparency and collaboration within the global organization.
Basic Qualifications:
We are looking for professionals with these required skills to achieve our goals:
- PhD with degree in Molecular Biology, Biotechnology, Bioengineering, Chemical Engineering or a related scientific field.
- A minimum of 6 years of industry experience on development of analytics on biomolecules, preferably nucleic acids.
- One or more years of experience in development activities required for CMC support.
Preferred Qualifications:
If you have the following characteristics, it would be a plus:
- Experience in Quality by Design.
- Knowledge of the large molecule regulatory environment, particularly FDA/ICH/ISPE guidelines on risk management, technology transfer and process validation.
- Effective leadership, people management and communication abilities in global environments.
- Exceptional proficiency in project management.
- Open, can-do and positive mindset is a must.
- Demonstrated Critical thinking ability.
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