What You Will Do:
We are currently searching for a Chemist to independently provide support services to satisfy the overall operational objectives of the National Center for Advancing Translational Sciences (NCATS), Therapeutics Development Branch (TDB). The target candidate needs experience related to chemical process development and scale-up synthesis activities and an understanding of Good Manufacturing Practices (GMP) concepts. This is a full-time, on-site opportunity in Rockville, MD.
- Perform synthetic route scouting.
- Perform process development of scale-up synthesis activities.
- Formulate chemistry plans for the development of soluble, potent, selective small molecule probes of biological function.
- Perform bulk-synthesis, purification, and formulation efforts for advanced testing in animal models.
- Maintain up-to-date electronic laboratory notebook detailing all experiments and associated online databases.
- Gather, analyze and interpret data; prepare summaries and reports.
- Search chemical databases for journal articles, patents and related technologies.
- Troubleshoot issues, maintain, and train users on scientific instrumentation and equipment.
- Prepare reagents and maintain an active inventory of all chemicals kept in the laboratory.
- Purify compounds by preparative chromatography.
- Perform chemical and biochemical reactions and appropriate analytical analyses, including chemical synthesis and optimization of small molecules probes and organic synthesis of key materials such as reference compounds.
- Analyze samples using validated analytical methods for ongoing studies.
- Develop and make recommendations on experimental procedures and research protocols including novel chemistry methodologies and technologies that advance the field and develop plans for novel syntheses and approaches to new compounds.
- Collaborate with staff to evaluate and/or develop new techniques.
What You Will Need:
- Master’s degree in chemistry.
- At least ONE (1) year of experience in a chemistry laboratory environment.
- Must have experience with either process development or scale-up synthesis activities.
- Must be familiar with common techniques such as Microscopy, Mass Spectrometry, Spectrophotometry, Chromatography technologies, X-Ray crystallography, or Thermal analytical technologies.
- MS Office suite.
What Would Be Nice To Have:
- Experience with Kilo Lab or pilot plant desired.
- Beneficial to be familiar with common microscopy techniques such as Confocal, Electron, Multi Photon, Fluorescence, or Super Resolution Nuclear Magnetic Resonance Microscopy.
- Beneficial to be familiar with common chromatography techniques such as HPLC, UPLC, GC, IC, or thin layer.
- Manuscript writing preferred.
Job Family: Biologist (Digital)
Travel Required: None
Clearance Required: Ability to Obtain Public Trust
Salary Range: $57,300.00-$85,900.00
What We Offer:
Guidehouse offers a comprehensive, total rewards package that includes competitive compensation and a flexible benefits package that reflects our commitment to creating a diverse and supportive workplace.
Benefits include:
- Medical, Rx, Dental & Vision Insurance
- Personal and Family Sick Time & Company Paid Holidays
- Parental Leave
- 401(k) Retirement Plan
- Group Term Life and Travel Assistance
- Voluntary Life and AD&D Insurance
- Health Savings Account, Health Care & Dependent Care Flexible Spending Accounts
- Transit and Parking Commuter Benefits
- Short-Term & Long-Term Disability
- Tuition Reimbursement, Personal Development, Certifications & Learning Opportunities
- Employee Referral Program
- Corporate Sponsored Events & Community Outreach
- Care.com annual membership
- Employee Assistance Program
- Supplemental Benefits via Corestream (Critical Care, Hospital Indemnity, Accident Insurance, Legal Assistance and ID theft protection, etc.)
- Position may be eligible for a discretionary variable incentive bonus
About Guidehouse
Guidehouse is a leading global provider of consulting services to the public sector and commercial markets, with broad capabilities in management, technology, and risk consulting. By combining our public and private sector expertise, we help clients address their most complex challenges and navigate significant regulatory pressures focusing on transformational change, business resiliency, and technology-driven innovation. Across a range of advisory, consulting, outsourcing, and digital services, we create scalable, innovative solutions that help our clients outwit complexity and position them for future growth and success.
The company has more than 16,000 professionals in over 55 locations globally. Guidehouse is led by seasoned professionals with proven and diverse expertise in traditional and emerging technologies, markets, and agenda-setting issues driving national and global economies.
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