We’re in relentless pursuit of breakthroughs that change patients’ lives. We innovate every day to make the world a healthier place.
To fully realize Pfizer’s purpose – Breakthroughs that change patients’ lives – we have established a clear set of expectations regarding “what” we need to achieve for patients and “how” we will go about achieving those goals.
Pfizer offers competitive compensation and benefits programs designed to meet the diverse needs of our colleagues.
Pfizer’s purpose is to deliver breakthroughs that change patients’ lives. Research and Development is at the heart of fulfilling Pfizer’s purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting-edge design and process development capabilities to accelerate and bring the best-in-class medicines to patients around the world.
What You Will Achieve
As a Scientist in the Antibody Discovery and Engineering team, you will be an integral member of a highly collaborative and cross-functional team, supporting antibody discovery and optimization platforms for the advancement of therapeutic antibody projects. You will design and execute key experiments to determine desirable antibody and ADC attributes and will actively engage in troubleshooting/implementing new workflows. With deep knowledge of the assays, you will perform insightful data analysis and present findings to your colleagues. Relying on extensive prior experience and literature sources, you will provide valuable scientific input to the team.
How You Will Achieve It
- Apply cell-based methodologies including multicolor flow cytometry, internalization and cytotoxicity assays to discovery research projects in the area of oncology.
- Execute biophysical characterization assays, including DSF, DLS and ELISA, to enable antibody lead selection.
- Design robust experiments to generate high quality, reproducible data.
- Proactively seek guidance and build knowledge relevant to the role.
- Maintain rigorous records of experimental progress using electronic laboratory notebooks.
Qualifications
- Bachelor's degree in biology, biochemistry, or related field and 6 years of relevant experience in the academic/biotech industry.
- Master's degree in biology, biochemistry, or related field and 4 years of relevant experience in the Academic/biotech/pharmaceutical industry.
- Strong understanding of antibody discovery platforms.
- Working knowledge of mammalian cell culture and cell-based assay development.
- Ability to prioritize and independently plan and execute experiments with minimal supervision.
- Strong data and time organization/management skills, attention to detail, and desire to achieve both team and individual goals.
- Ability to communicate effectively with colleagues at all levels.
Nice-to-Have
- Expertise performing and troubleshooting binding assays, including BLI, and SPR.
- Familiarity with developability and biophysical characterization assays.
- Understanding of cancer biology and experience with oncology drug development.
- Experience with high throughput and automated lab equipment and assays.
PHYSICAL/MENTAL REQUIREMENTS
- Lifting, sitting, standing, walking, bending, ability to perform mathematical calculations and ability to perform complex data analysis.
- Must be able to wear specialized protective clothing and PPE (lab coat, safety shoes/glasses/etc).
Additional Information:
- Relocation Assistance Available.
- Eligible for Employee Referral.
- Last Day to Apply: October 25, 2024.
The annual base salary for this position ranges from $74,900.00 to $124,800.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 7.5% of the base salary. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
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