Clinical Flow Cytometry Scientist (Contract)
Groton, CT, United States (On-site)
Contract (17 months 29 days)
Published 2 days ago
Summary:
The Regulated Clinical Biomarker/Flow Cytometry group works with clinical and translational teams across Pfizer research units to develop and implement complex flow cytometry-based biomarker assays and supportive translational/mechanistic studies for early-phase clinical projects in a GCLP environment. This position is responsible for the execution of scientific research and/or scientific strategies in a biomarker/biomeasure-focused flow cytometry laboratory. This scientist will provide technical and scientific support for biomarker data using flow cytometry (FACs), cell imaging, and related technologies for both non-regulated and regulated clinical biomarker studies supporting Pfizer drug candidates. This scientist will interact with inter-departmental colleagues, clinical and translational teams, research units, and contract research organizations in a matrixed environment.
Responsibilities:
- Responsible for clinical flow cytometry biomarker assay development and validation, data generation and analysis, QC, data interpretation, and communication to project teams to enable appropriate decision-making.
- Participate with ECD teams and research units in a matrix environment, demonstrating experience in the delivery of flow cytometry and cell imaging-based biomarkers/biomeasures in clinical studies, with strong knowledge of biological systems, cellular functions, and concepts in immunology to enable Pfizer discovery and development objectives.
- Develop partnerships in a matrix environment, influencing project strategies and providing expertise in technology development and implementation.
- Participate in all phases of FACs laboratory operations including technology evaluations, development of sample preparation, separation and detection methods, data analysis, interpretation, reporting, and follow-up discussions with project teams on utilizing the data in appropriate decision-making.
- Maintain regulatory compliance appropriate for clinical study execution including all proscribed training as found in ECD SOPs and training transcripts, with knowledge and understanding of GLP/GCP guidance for execution of preclinical and clinical studies supporting Pfizer portfolio projects.
- Participate in continuous improvement of scientific and regulatory processes via update/creation of SOPs, design and implementation of laboratory and study-based processes, and development of best practices for bioanalytical data generation.
- Responsible for QC and peer review of raw data, results, and final reports from other colleagues within the regulated group (depending on level of training). Participate in internal and external audits providing required information to auditors as needed, and may also participate/respond to internal audit findings on assigned projects.
Qualifications:
- Bachelor's degree with a minimum of 3+ years of laboratory experience (can be educational experience).
- Demonstrated experience in the delivery of flow cytometry and cell imaging-based biomarkers/biomeasures in clinical studies.
- Strong knowledge of biological systems, cellular functions, and concepts in immunology.
- Prior flow cytometry experience preferred.
- GCLP experience preferred.
Rate/Location:
- $32 - $42 per hour
- This is a fully onsite role in Groton, CT.
- Monday - Friday; 1st shift (occasional weekend work for processing clinical samples should be anticipated).
Please note contractors are engaged to provide services to Pfizer temporarily in connection with a specific assignment. Contractors are hired and employed through Atrium, our third-party payrolling partner.
This job posting is for a temporary role as an employee of Atrium on assignment at Pfizer. The individual selected for this role will be offered the role as an employee of Atrium; compensation, medical benefits, fringe benefits, and other terms and conditions of employment shall be presented by Atrium upon offer. The pay rate range provided is a reasonable estimate of the anticipated compensation range for this job at the time of posting. The actual pay rate will be based on several factors, including skills, competencies, experience, location and/or being pursued, and other job-related factors permitted by law. In addition, this role will be eligible for overtime pay, in accordance with federal and state requirements.
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