If you are interested in this job opportunity, please apply at: Zai Lab Job Application
Company Description
Zai Lab Limited (NASDAQ: ZLAB; HKEX: 9688) is an innovative, research-based, commercial-stage biopharmaceutical company based in China and the United States focused on bringing transformative medicines for oncology, autoimmune disorders, infectious diseases, and neurological disorders to patients in China and around the world.
Founded in 2014, our experienced team has secured partnerships with leading global biopharmaceutical companies, generating a broad and late-stage pipeline of innovative drug candidates. Zai Lab has earned the reputation as a trusted partner of choice for global biopharmaceutical companies seeking to access the Chinese market and find a long-term strategic partner for global clinical development.
Zai Lab was successfully listed on the Nasdaq Stock Market in September 2017 and completed a secondary listing on the Hong Kong Stock Exchange in September 2020. As of January 2022, the Company has a global team of approximately 2000 employees.
Job Description
This Director of Cancer Biology will lead small molecule discovery project(s) from target identification/validation to delivery of development candidate. This role will provide scientific and technical expertise to understand the mechanism of action (MOA) and biology rationale to guide the selection of promising targets in the oncology space; manage external FTEs or studies carried out externally to ensure the delivery of high-quality results; and support the BD team in evaluating in-license and partnership opportunities.
- Identify and integrate technologies that improve or expand the ability to assess the mechanism of action of novel anticancer agents.
- Lead an internal/external team of scientists in designing and executing cancer biology experiments to assess mode of action and therapeutic potential of novel or validated cancer targets.
- Ensure timely delivery of biology data to support key decision-making.
- Identify appropriate animal models and execute pharmacology studies to support discovery projects.
- Actively contribute to oncology drug discovery research programs, including identification and validation of new targets.
- Support identification and prioritization of high-impact research activities.
- Establish and manage relationships with external research collaborators and CROs.
- Ensure the high quality of research conducted externally at CROs and provide guidance to maintain high productivity.
- Support BD team to identify high-value in-license and collaboration opportunities.
Qualifications
REQUIRED:
- PhD with postdoctoral training and 5 years of relevant pharma or biotech industry experience managing programs in the field of oncology; or equivalent combination of higher education, training, and experience.
PREFERRED:
- Proven track record of success in oncology or related fields demonstrated by strong publication record (first author papers in high-impact journals).
- Current knowledge of oncology research, drug discovery and development, with emphasis on DNA damage repair (DDR) and cell apoptosis pathways.
- Creativity to design and engineer complex assays that address target-specific biology.
- Great attention to detail with the ability to multitask.
- Collaborative and team-oriented, possessing excellent oral and written communication and organizational skills.
Additional Information
The pay range for this position at the commencement of employment is expected to be between $215k and $251k/year; however, base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience.
At Zai, we are proud of the gender diversity of our company and our promotion of women in biotech. We are committed to the health of patients and our planet.
All qualified applicants will receive consideration for employment without regard to race, sex, color, religion, sexual orientation, gender identity, national origin, protected veteran status, or based on disability.
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