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Job Category: Staff & Executive - Research Support (Laboratory/Non-Laboratory)
Department: RWJ-Biochemistry & Molecular Biology
Overview:
New Jersey’s academic health center, Rutgers Biomedical and Health Sciences (RBHS) takes an integrated approach to educating students, providing clinical care, and conducting research, all with the goal of improving human health. Aligned with Rutgers University–New Brunswick and collaborating university-wide, RBHS includes eight schools, a behavioral health network, and six centers and institutes that focus on cancer treatment and research, neuroscience, clinical and translational research, advanced biotechnology and medicine, environmental and occupational health, and health care policy and aging research.
The Mickolajczyk laboratory (https://sites.rutgers.edu/mickolajczyk-lab/) is recruiting Post Doctoral Associates to engage in ongoing research projects relative to studying the mechanisms of pre-ribosome maturation by motor proteins and regulation and substrate-targeting by ATPase enzymes in ribosome biogenesis.
The main project involves studying the mechanisms of pre-ribosome maturation by motor proteins, an essential process for generating new ribosomes that are properly folded and competent for protein translation. Force spectroscopy (optical and magnetic tweezers), single-molecule fluorescence, and bulk biochemical methods will be used to investigate how these motor proteins convert the energy from ATP hydrolysis into mechanical work in order to promote pre-ribosomal folding. The assays developed will be used to benchmark wildtype versus disease-derived mutants of motor proteins to investigate the molecular bases of ribosomopathies and other ribosome-dependent diseases. The Post Doctoral Associate will also have the opportunity to participate in ongoing collaborative projects, as well as to spearhead new projects within the lab.
Among the key duties of this position are the following:
- Engage in scientific communication, training of junior personnel, grant writing, and manuscript preparation.
- Participate in the evaluation of existing procedures, suggesting revisions where necessary and proposing new procedures where required.
- Contribute to the development of performance standards, selection of methodology and instrumentation, and coordination of the analytical, biochemical, physiology and instrumentation functions with the research areas to ensure conformance with the goals and objectives of the department.
- Maintain accurate records of laboratory notebooks and research activity. Review literature and prepare manuscripts and abstracts for submission. Present findings at national meetings.
- May also mentor graduate/undergraduate students.
Position Status: Full Time
Daily Work Shift: Day
Work Arrangement: This position requires a fully on-site work arrangement.
Minimum Education and Experience:
- The candidate requires a post-doctoral degree by the start of employment; preferably in biochemistry, biophysics, bioengineering, or similar within life sciences, and significant experience in biochemical and molecular biology methods to study proteins and RNA.
Required Knowledge, Skills, and Abilities:
- The ideal candidate is energetic, collegial, detail-oriented, and organized.
Preferred Qualifications:
- Preference would be for the candidate to have earned the PhD within the past 3 years.
- Previous experience in single-molecule biophysics.
Physical Demands and Work Environment:
- Physical Demands: Standing, sitting, walking, talking, or hearing. No special vision requirements.
- Work Environment: Lab environment with moderate noise. Radioactivity and hazardous chemicals are used in the lab.
Special Conditions:
All offers of employment are contingent upon successful completion of all pre-employment screenings. Immunization Requirements: Under Policy 100.3.1 Immunization Policy for Covered Individuals, if employment will commence during Flu Season, Rutgers University may require certain prospective employees to provide proof that they are vaccinated against Seasonal Influenza for the current Flu Season, unless the University has granted the individual a medical or religious exemption.
Supplemental Questions
Required fields are indicated with an asterisk (*).
- * Do you have a post-doctoral degree in biochemistry, biophysics, bioengineering, or similar within life sciences?
Required Documents:Optional Documents:- Cover Letter/Letter of Application
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