Company Description
AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com.
Job Description
Bioinformatics for Neuroscience Intern Overview
Envision spending your summer working with energetic colleagues and inspirational leaders, all while gaining world-class experience in one of the most dynamic organizations in the pharmaceutical industry. This is a reality for AbbVie Interns.
The Bioinformatics for Neuroscience intern will work with the Neuroscience Bioinformatics team of the Genomics Research Center (GRC) at AbbVie. The GRC is a multidisciplinary center of excellence with expertise in genomic technologies and their application, human genetics, genomic medicine, computational analysis, data integration, genome biology, and application of functional genomics.
The internship project will focus on target identification for Alzheimer’s Disease through a deep dive into brain cell type specific eQTL information. This project will involve:
- Collecting datasets: microglia relevant variants from our internal eQTL study and microglia promoter-capture Hi-C from manuscript
- Analysis: identify variants that are eQTLs, extending to disease specific or microglia subtype specific, and perform colocalization analysis under the assumption of more than one casual variant
- Analysis: filter variants that overlap with peaks in Hi-C and identify risk genes associated with the promoters
- Filtering: shortlist relevant genes by using information from other single-nuclei RNAseq and consortium studies
- Pitch: share results with Neuroscience stakeholders to do a deep dive on the prioritized targets and perform knock-out experiments in microglia to understand the biology and pathways involved
Qualifications
Minimum Qualifications
- Currently enrolled in university, pursuing a PhD in Bioinformatics, Computational Biology or other related field
- Must be enrolled in university for at least one semester following the internship
- Knowledge in R or Python programming
- Strong written, verbal and oral communication skills, good self-organization
- Strong quantitative and analytical skills
Preferred Qualifications
- Expected graduation date between December 2025 – July 2026
- Exposure to eQTL and chromatin conformation data analysis
- Exposure to neuroscience projects
Benefits and Amenities
- Competitive pay
- Relocation support for eligible students
- Select wellness benefits and paid holiday / sick time
- Opportunity to connect with Abbvie leaders and scientists
- Exposure to cutting edge discovery concepts and technologies
Equal Employment Opportunity
At AbbVie, we value bringing together individuals from diverse backgrounds to develop new and innovative solutions for patients. As an equal opportunity employer we do not discriminate on the basis of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information gender identity or expression, sexual orientation, marital status, protected veteran status, or any other legally protected characteristic.
Salary: $58,656 - $98,000
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