Principal Pathologist - Preclinical Safety
AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on Twitter, Facebook, Instagram, YouTube, and LinkedIn.
Job Description
The Department of Pathology in Preclinical Safety at AbbVie has an opening for a board-certified veterinary anatomic pathologist working in toxicologic pathology with an interest in digital pathology and AI. The primary role of the pathologist is to assess the safety profile of experimental compounds in a variety of nonclinical species through evaluation of clinical and anatomic pathology data, presentation of data, and preparation of reports. These data enable project teams to de-risk and advance candidate compounds through early to late stages of development. The candidate will also help develop cutting-edge automation and AI technologies for increased efficiency and deeper insights, which helps ensure the safety of medicines reaching patients. The successful candidate will be scientifically curious, a consensus builder, and strive to deliver meticulous and data-driven solutions to create optimal outcomes for patients.
Responsibilities
- Evaluates exploratory and regulated nonclinical toxicity studies to determine the potential toxicity of experimental compounds in different nonclinical species, based on interpretation of pathology data (e.g., necropsy, histopathology, clinical pathology, electron microscopy, IHC).
- Perform pathology peer reviews.
- Provides scientific and technical expertise to interdisciplinary teams working on image analysis projects, including database curation and novel AI model development.
- Integrates the anatomic pathology data, clinical pathology data, and other study findings to generate a pathology report as a component of the toxicology report.
- Provides input to study design, supervises necropsies, performs histological examinations in rodent and non-rodent studies, authors pathology reports, conducts peer reviews, and reviews regulatory documents.
- Partners with data scientists, toxicologists, pharmacologists, and CRO partners to develop optimal strategies to address specific toxicology issues and rapidly prioritize the safest compounds for progression through development.
Qualifications
- Doctor of Veterinary Medicine (DVM or equivalent)
- Board Certification in Veterinary Anatomic Pathology (ACVP or equivalent)
- Candidates with a Ph.D. in pathology or related discipline are preferred.
- Familiarity with related fields: pharmacology, toxicology, and drug development.
- Experience with digital histology image analysis principles and platforms.
- Ability to plan, organize, troubleshoot, interpret, and present findings independently.
Additional Information
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:
The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance, and 401(k) to eligible employees.
This job is eligible to participate in our short-term incentive programs.
This job is eligible to participate in our long-term incentive programs.
Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remain in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.
AbbVie is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion. It is AbbVie’s policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status.
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