Principal Scientist, DMPK Advisory Services
Position Summary:
Catalent is a global, high-growth, public company and a leading partner for the pharmaceutical industry in the development and manufacturing of new treatments for patients worldwide. Your talents, ideas, and passion are essential to our mission: to help people live better, healthier lives.
This is a full-time salaried position: Monday – Friday, 1st shift.
Our Somerset location is the corporate headquarters for Catalent Pharma Solutions. This location houses our state-of-the-art laboratory, clinical, and commercial manufacturing plant for oral dose forms in addition to being the Center of Excellence for Highly Potent Active Pharmaceutical Ingredients.
The Principal Scientist, Drug Metabolism & Pharmacokinetics (DMPK) Advisory Services, will lead and execute Pharmacokinetic modeling for the US region and support PK modeling for other regions, leveraging the internal scientific community and external collaborations to drive Catalent’s brand for drug delivery technologies.
The Role:
- Perform in silico modeling to model drug absorption in various animal species to select the most appropriate molecules for evaluation as a drug and to confirm the viability of dosing routes.
- Based on in vitro and in vivo data, perform in silico modeling to estimate the rate and extent of absorption of drug molecules from at least three human dosing routes.
- By applying absorption models, evaluate the effect of modified release on the rate and extent of absorption to mitigate dose frequency, efficacy, and toxicity limitations.
- Perform modeling in specific patient populations (e.g., pediatric, geriatric, or special patient populations) upon request.
- Partner with Business Development in the US region for new and existing business opportunities for assigned projects or technologies.
- Participate in the creation of Catalent Scientific Advisory strategy.
- Participate in the creation and execution of Catalent scientific editorial line.
- Support assigned Product Development efforts in the region.
- Other duties as assigned.
The Candidate:
- Bachelor’s Degree in Life Sciences, required.
- Seven+ years of experience in the pharmaceutical industry and five+ years of PBPK modeling, required.
- Thorough expertise in Gastro plus and PBPK modeling.
- Experience in biopharmaceutics and bioavailability enabling technologies, preferred.
- Experience in multiple market segments (Rx) and unit dosage forms, with a strong background in solving poor bioavailability issues and modified release.
- Up to 15% travel expectations (globally).
- Individual may be required to sit, stand, walk regularly, and occasionally lift 0-15 pounds.
Why You Should Join Catalent:
- Defined career path and annual performance review and feedback process.
- Diverse, inclusive culture.
- 152 hours of PTO + 8 paid holidays.
- Several Employee Resource Groups focusing on D&I.
- Dynamic, fast-paced work environment.
- Positive working environment focusing on continually improving processes to remain innovative.
- Potential for career growth on an expanding team within an organization dedicated to preserving and bettering lives.
- Community engagement and green initiatives.
- Generous 401K match.
- Medical, dental, and vision benefits effective day one of employment.
- Tuition Reimbursement.
- WellHub - program to promote overall physical wellness.
- Perkspot - offers exclusive or private discounts from approximately 900+ merchants in a wide array of categories.
Catalent offers rewarding opportunities to further your career! Join the global drug development and delivery leader and help us bring over 7,000 life-saving and life-enhancing products to patients around the world.
Catalent is an Equal Opportunity Employer, including disability and veterans.
If you require reasonable accommodation for any part of the application or hiring process due to a disability, you may submit your request by sending an email to DisabilityAccommodations@catalent.com.
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