We are seeking a staff scientist to join the Fabbri Lab. Research projects will focus on the role of microRNAs and other non-coding RNAs in the tumor microenvironment (TME). We study how non-coding RNAs in extracellular vesicles affect cancer biology and how this knowledge can lead to the development of new anti-cancer therapies through CRISPR-drug screening. Candidates are expected to be familiar with the following techniques: cell culture, transfections, cloning, DNA and RNA isolation, immunoblotting, PCR, real-time PCR, MTT assays, cytofluorimetry, CRISPR gene editing. In vivo experience with cancer mouse models (xenografts or orthotopic models) is required. Knowledge of statistics for data analysis and interpretation is desirable. Candidates should be able to design and execute laboratory experiments, interpret experimental results, work well in a team environment, contribute to weekly lab meetings, and present data in a clear and concise manner.
The Staff Scientist III position is a senior role requiring a PhD degree and reporting to a principal investigator or CNRI center director. This position requires a high level of professionalism and expertise and will serve in several roles in the research center depending on the scientific specialty and the needs of the laboratory. The Staff Scientist III creates opportunities to enhance technical methodology or content through the expansion of existing or development of new efforts, and may extend technology into new application areas. The Staff Scientist III supervises junior scientists, graduate students, and technicians and works independently or with technical guidance from the principal investigator.
Qualifications
Minimum Education: Doctor of Philosophy (Ph.D.) (Required)
Minimum Work Experience: 8 years Progressive specialized experience in a field of research (Required)
Required Skills/Knowledge: Experience must demonstrate that the applicant has acquired the scientific knowledge, skills, and abilities to apply and utilize successfully in independent health or health-related research appropriate to the position. Comprehensive knowledge of a particular field and the ability to apply that knowledge to the completion of complex assignments. Ability to advance state-of-the-art research in the field of specialization.
Functional Accountabilities
- Responsible Conduct of Research:
- Consistently demonstrates adherence to the standards for the responsible conduct of research.
- Plans, conducts, and manages research projects within federal and institutional regulations and policies under the direction of the principal investigator.
- Uses research funds and resources appropriately.
- Maintains confidentiality of data as required.
- Meets all annual job-related training and compliance requirements.
Research:- Conducts research of significant scientific value in the basic and/or translational science areas relevant to practice specialty.
- Participates in reviewing manuscripts for peer-reviewed journals.
- Publishes in peer-reviewed, scientific, quality and management journals.
- Submits applications for grants or contracts for funding of research projects.
- Collects, codes, and compiles statistics (coding of data requires interpretation of data from a broad range of alternatives).
Leadership and Collaboration:- Contributes to or leads in major intellectual development activities.
- Mentors graduate/post-doctoral students.
- Participates in educational programs, teaching assignments, technical meetings, workshops, and committees.
- Creates opportunities to enhance technical methodology or content through the expansion of existing or development of new efforts.
- Assists with the management of resource allocations and manages day-to-day activities in the laboratory, such as purchasing, oversight of laboratory animals, radioactivity, and biosafety issues.
- Applies innovative problem-solving approaches to enhance organizational capabilities and uses peer network to expand technical capabilities and identify new research opportunities in collaboration with the principal investigator.
Reports, Proposals, and Publications:- Generates standard and ad-hoc reports as needed.
- Analyzes and evaluates data.
- Develops and modifies databases as needed.
- Compiles data and writes sections of project results and analysis.
- Edits sections written by colleagues.
- Prepares charts and graphs for publication.
- Drafts and edits manuscripts and grant proposals.
Organizational Accountabilities
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