Working with Us
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.
Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.
The molecular Principal Scientist role is responsible for developing molecular assays and generation of research use genomics data in support of BMS clinical trial analysis. This includes but is not limited to responsibility for genomics and gene expression profiling (GEP) biomarker assay technology/ platform selection, evaluation of in-house or vendor choice per assay use requirements, development, optimization, qualification/validation and/or execution of biomarker analysis for BMS translational medicine and clinical programs.
This position is 100% lab focused requiring onsite attendance.
The individual is expected to work on multiple projects to support translational medicine and clinical programs. The individual works on genomics/transcriptomics strategy (assay, platform) per program requirements, protocol requirements, program biology and mechanism. Assays include but are not limited to broad genomic/GEP profiling, pharmacodynamic assays, target engagement assays, predictive, prognostic assays and technology platform development.
Key Responsibilities:
- Develop the framework for assay development, qualification/validation protocols and timely, well-planned execution of assay and clinical analysis working with cross-functional teams.
- Assist with troubleshooting of any assay performance-related activities.
- Facilitate the design, develop, optimize genomics and genetics biomarker assays and develop and execute the qualification/validation of these assays for clinical trial assays in house and/or potentially with external vendors.
- Oversee assay/workflow development and generation/analysis of qualification/validation data.
- Draft experimental plans, including qualification protocols and reports, work instructions/SOPs, technology transfer documents, and study reports or summaries.
- Actively participate in internal/external collaboration and clinical study and biomarker execution teams as appropriate.
- Provide subject matter expertise for functional lead stakeholders as required.
- Accurate record keeping of experiments and procedures.
- Act as a technology evangelist and help assess and onboard relevant technologies working with matrixed teams per program requirements.
- Provide mentorship and leadership within the MAD lab team.
Basic Qualifications:
- Bachelor’s Degree with 8+ years of academic and/or industry experience
- Or Master’s Degree with 6+ years of academic and/or industry experience
- Or Ph.D. or equivalent advanced degree in the Life Sciences with 4+ years of academic and/or industry experience
Preferred Qualifications:
- Significant experience and subject matter expertise in PCR, NGS or GEP application, significant technology and lab experience is a must.
- Experience in clinical assay development for genomics assets preferably in a pharma, biotech, diagnostic or clinical lab setting.
- Expertise in developing assays, overseeing assay validation, and developing appropriate controls/QC methodology.
- Experience with additional technologies leveraged for ctDNA analysis and GEP analysis.
- Understanding of fit for purpose genomics assay validation principles for clinical assays.
- Strong organizational, communication, interpersonal and collaborative skills.
- Excellent leadership and mentoring qualities for technical team and matrixed team.
If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.
Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as “Transforming patients’ lives through science”, every BMS employee plays an integral role in work that goes far beyond ordinary.
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